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Role of ST-Segment Resolution in Patients With ST-Segment Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention (from the 5-Year Outcomes of the EXAMINATION [Evaluation of the Xience-V Stent in Acute Myocardial Infarction] Trial)
- Source :
- AMERICAN JOURNAL OF CARDIOLOGY, r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante, instname, r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
- Publication Year :
- 2018
- Publisher :
- Elsevier BV, 2018.
-
Abstract
- In patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI), lack of ST-segment resolution (STR) is associated with poor prognosis at short- and long-term follow-up. The aim of this study was to evaluate the role of STR on very long-term outcomes in patients with STEMI treated with pPCI included in the EXAMINATION (Evaluation of the Xience-V Stent in Acute Myocardial Infarction) trial. Patients were stratified according to the presence of STR 50% and STR >= 70%, respectively. In both cases, this difference was mainly driven by a significant increase in the rate of all-cause death and any revascularization. After multivariable adjustment, STR < 70%, but not STR < 50%, resulted as a 5-year independent predictor of POCE (adjusted HR 1.338, 95% CI 1.008 to 1.778, p = 0.044). In conclusion, in patients with STEM!, the evaluation of 70% STR after pPCI provides independent prognostic information at 5-year follow-up and it can be used to identify patients at high risk of very long-term cardiovascular events. (C) 2018 Elsevier Inc. All rights reserved.
- Subjects :
- Male
medicine.medical_treatment
Myocardial Infarction
030204 cardiovascular system & hematology
Electrocardiography
0302 clinical medicine
Cause of Death
Drug-Eluting Stent
Myocardial Revascularization
ST segment
030212 general & internal medicine
Myocardial infarction
610 Medicine & health
Drug-Eluting Stents
Middle Aged
Prognosis
humanities
Treatment Outcome
Cardiology
Female
Cardiology and Cardiovascular Medicine
geographic locations
Human
congenital, hereditary, and neonatal diseases and abnormalities
medicine.medical_specialty
Poor prognosis
Prognosi
Revascularization
Independent predictor
NO
03 medical and health sciences
Percutaneous Coronary Intervention
Internal medicine
medicine
Humans
In patient
cardiovascular diseases
Mortality
Aged
Proportional Hazards Models
business.industry
Percutaneous coronary intervention
Stent
Recovery of Function
social sciences
medicine.disease
eye diseases
Proportional Hazards Model
ST Elevation Myocardial Infarction
business
Subjects
Details
- ISSN :
- 00029149
- Volume :
- 121
- Database :
- OpenAIRE
- Journal :
- The American Journal of Cardiology
- Accession number :
- edsair.doi.dedup.....9d25e2a7a2f5c3698a1d71cabe037a4f