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GET.ON Mood Enhancer: efficacy of Internet-based guided self-help compared to psychoeducation for depression: an investigator-blinded randomised controlled trial
- Source :
- Ebert, D D, Lehr, D, Baumeister, H, BoB, L, Riper, H, Cuijpers, P, Reins, J A, Buntrock, C & Berking, M 2014, ' GET.ON Mood Enhancer: efficacy of Internet-based guided self-help compared to psychoeducation for depression: an investigator-blinded randomised controlled trial ', Trials, vol. 15, 39 . https://doi.org/10.1186/1745-6215-15-39, Trials, Ebert, D D, Lehr, D, Baumeister, H, Boß, L, Riper, H, Cuijpers, P, Reins, J A, Buntrock, C & Berking, M 2014, ' GET.ON Mood Enhancer : Efficacy of Internet-based guided self-help compared to psychoeducation for depression: An investigator-blinded randomised controlled trial ' Trials, vol 15, no. 1, 39 . DOI: 10.1186/1745-6215-15-39, Trials, 15:39. BioMed Central, Ebert, D D, Lehr, D, Baumeister, H, Boß, L, Riper, H, Cuijpers, P, Reins, J A, Buntrock, C & Berking, M 2014, ' GET.ON Mood Enhancer : Efficacy of Internet-based guided self-help compared to psychoeducation for depression: An investigator-blinded randomised controlled trial ', Trials, vol. 15, no. 1, 39 . https://doi.org/10.1186/1745-6215-15-39
- Publication Year :
- 2014
-
Abstract
- Background: Major depressive disorder (MDD) imposes a considerable disease burden on individuals and societies. A large number of randomised controlled trials (RCTs) have shown the efficacy of Internet-based guided self-help interventions in reducing symptoms of depression. However, study quality varies considerably. The aim of this study is to evaluate the efficacy of a new Internet-based guided self-help intervention (GET.ON Mood Enhancer) compared to online-based psychoeducation in an investigator-blinded RCT.Methods/design: A RCT will be conducted to compare the efficacy of GET.ON Mood Enhancer with an active control condition receiving online psychoeducation on depression (OPD). Both treatment groups will have full access to treatment as usual. Adults with MDD (n = 128) will be recruited and randomised to one of the two conditions. Primary outcome will be observer-rated depressive symptoms (HRSD-24) by independent assessors blind to treatment conditions. Secondary outcomes include changes in self-reported depressive symptom severity, anxiety and quality of life. Additionally, potential negative effects of the treatments will systematically be evaluated on several dimensions (for example, symptom deteriorations, attitudes toward seeking psychological help, relationships and stigmatisation). Assessments will take place at baseline, 6 and 12 weeks after randomisation.Discussion: This study evaluates a new Internet-based guided self-help intervention for depression using an active control condition (psychoeducation-control) and an independent, blinded outcome evaluation. This study will further enhance the evidence for Internet-based guided self-help interventions for MDD.Trial registration: German Clinical Trial Registration (DRKS): DRKS00005025. © 2014 Ebert et al.; licensee BioMed Central Ltd.
- Subjects :
- Research design
Health Knowledge, Attitudes, Practice
Time Factors
Negative effects of psychotherapy
medicine.medical_treatment
Psychological intervention
Medicine (miscellaneous)
Severity of Illness Index
law.invention
Study Protocol
Clinical Protocols
Randomized controlled trial
law
Germany
Surveys and Questionnaires
Psychology
Single-Blind Method
Pharmacology (medical)
Randomised controlled trial
Internet-based
Treatment Outcome
Research Design
Major depressive disorder
Anxiety
medicine.symptom
medicine.medical_specialty
Guided self-help
Patient Education as Topic
SDG 3 - Good Health and Well-being
medicine
Psychoeducation
Humans
Psychiatry
Psychiatric Status Rating Scales
Depressive Disorder, Major
Internet
business.industry
Health sciences
medicine.disease
Psychotherapy
Clinical trial
Affect
Mood
Therapy, Computer-Assisted
Quality of Life
Active control
business
Subjects
Details
- Language :
- English
- ISSN :
- 17456215
- Database :
- OpenAIRE
- Journal :
- Ebert, D D, Lehr, D, Baumeister, H, BoB, L, Riper, H, Cuijpers, P, Reins, J A, Buntrock, C & Berking, M 2014, ' GET.ON Mood Enhancer: efficacy of Internet-based guided self-help compared to psychoeducation for depression: an investigator-blinded randomised controlled trial ', Trials, vol. 15, 39 . https://doi.org/10.1186/1745-6215-15-39, Trials, Ebert, D D, Lehr, D, Baumeister, H, Boß, L, Riper, H, Cuijpers, P, Reins, J A, Buntrock, C & Berking, M 2014, ' GET.ON Mood Enhancer : Efficacy of Internet-based guided self-help compared to psychoeducation for depression: An investigator-blinded randomised controlled trial ' Trials, vol 15, no. 1, 39 . DOI: 10.1186/1745-6215-15-39, Trials, 15:39. BioMed Central, Ebert, D D, Lehr, D, Baumeister, H, Boß, L, Riper, H, Cuijpers, P, Reins, J A, Buntrock, C & Berking, M 2014, ' GET.ON Mood Enhancer : Efficacy of Internet-based guided self-help compared to psychoeducation for depression: An investigator-blinded randomised controlled trial ', Trials, vol. 15, no. 1, 39 . https://doi.org/10.1186/1745-6215-15-39
- Accession number :
- edsair.doi.dedup.....9d3a1e93e8f930e4453c44f21a899104
- Full Text :
- https://doi.org/10.1186/1745-6215-15-39