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Anthropometry and head and neck cancer:a pooled analysis of cohort data

Authors :
Aimée R. Kreimer
Aimee A. D’Aloisio
Laura E. Beane Freeman
Peggy Reynolds
Mark P. Purdue
Anna E. Prizment
Alicja Wolk
Anne Zelenuich-Jacquotte
Mia M. Gaudet
Howard D. Sesso
Alpa V. Patel
Elio Riboli
Dale P. Sandler
Gong Yang
Wei Zheng
Emily White
Anil K. Chaturvedi
Leslie Bernstein
Cari M. Kitahara
Martha S. Linet
I-Min Lee
Yu Chen
Elisabete Weiderpass
Christina C. Newton
Julie E. Buring
Yong-Bing Xiang
M. Freedman
Susan M. Gapstur
Wen Yi Huang
Yikyung Park
Xiao-Ou Shu
Heiner Boeing
Kim Robien
Niclas Håkansson
Michael C. R. Alavanja
Graham G. Giles
J. Michael Gaziano
Patricia Hartge
Amy Berrington de Gonzalez
Hans-Olov Adami
Robert J. MacInnis
Yu-Tang Gao
Catherine Schairer
Source :
International Journal of Epidemiology. 44:673-681
Publication Year :
2015
Publisher :
Oxford University Press (OUP), 2015.

Abstract

Background: Associations between anthropometry and head and neck cancer (HNC) risk are inconsistent. We aimed to evaluate these associations while minimizing biases found in previous studies. Methods: We pooled data from 1 941 300 participants, including 3760 cases, in 20 cohort studies and used multivariable-adjusted Cox proportional hazard regression models to estimate hazard ratios (HR) and 95% confidence intervals (CI) for the association of anthropometric measures with HNC risk overall and stratified by smoking status. Results: Greater waist circumference (per 5 cm: HR = 1.04, 95% CI 1.03–1.05, P-value for trend =

Details

ISSN :
14643685 and 03005771
Volume :
44
Database :
OpenAIRE
Journal :
International Journal of Epidemiology
Accession number :
edsair.doi.dedup.....9d58c12a1474d2dfd0aeca2cb705ed7d