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Implementation of Pharmacogenetics at Cincinnati Children's Hospital Medical Center: Lessons Learned Over 14 Years of Personalizing Medicine
- Source :
- Clinical Pharmacology & Therapeutics. 105:49-52
- Publication Year :
- 2018
- Publisher :
- Wiley, 2018.
-
Abstract
- Significant inter-individual variability in medication response can result in adverse drug reactions (ADRs) and increased health care costs. Based on ADR prevalence and mounting evidence linking genetics and pharmacokinetic variability, Cincinnati Children’s Hospital Medical Center (CCHMC) launched the Genetic Pharmacology Service (GPS) in 2004 and has since performed >25,000 tests. Herein, we describe how the service developed, launched, and has been updated along with how it is currently utilized, and key lessons learned.
- Subjects :
- medicine.medical_specialty
Time Factors
Drug-Related Side Effects and Adverse Reactions
education
030226 pharmacology & pharmacy
Article
03 medical and health sciences
0302 clinical medicine
Health care
Humans
Medicine
Pharmacology (medical)
Drug reaction
Precision Medicine
Program Development
health care economics and organizations
Ohio
Pharmacology
business.industry
Hospitals, Pediatric
Pharmacogenetics
030220 oncology & carcinogenesis
Family medicine
Medication response
business
Subjects
Details
- ISSN :
- 15326535 and 00099236
- Volume :
- 105
- Database :
- OpenAIRE
- Journal :
- Clinical Pharmacology & Therapeutics
- Accession number :
- edsair.doi.dedup.....9db1c657a9f42449317937479073f999
- Full Text :
- https://doi.org/10.1002/cpt.1165