Intrauterine manipulation does not adversely influence the direction and frequency of endometrial waves

Objective To investigate whether intrauterine manipulation affects the direction or alters the frequency of endometrial wavelike activity. Design Prospective observational study. Setting University hospital–based fertility clinic. Patient(s) Thirty-six patients undergoing intrauterine insemination (IUI). Intervention(s) Ultrasound observation before and after IUI. Main Outcome Measure(s) Endometrial wave type and endometrial wave frequency before and after IUI. Result(s) There was no difference in the direction and frequency of endometrial waves before and after IUI in 36 patients. Conclusion(s) Although the induction of uterine contractions by intrauterine manipulation has been suggested in the literature, the present study shows no contractions or induction of unfavorable (fundus to cervix) endometrial wavelike activity in 36 patients undergoing IUI.