Back to Search
Start Over
Reply to Guy et al.: Support for a bottleneck in the 2011 Escherichia coli O104:H4 outbreak in Germany
- Source :
- Proceedings of the National Academy of Sciences of the United States of America, Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2012, 109 (52), pp.E3629-30. ⟨10.1073/pnas.1209419110⟩, Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (52), pp.E3629-30. ⟨10.1073/pnas.1209419110⟩, Grad, Y H, Lipsitch, M, Griggs, A D, Haas, B J, Shea, T P, McCowan, C, Montmayeur, A, FitzGerald, M, Wortman, J R, Krogfelt, K A, Bingen, E, Weill, F-X, Tietze, E, Flieger, A, Lander, E S, Nusbaum, C, Birren, B W, Hung, D T & Hanage, W P 2012, ' Reply to Guy et al.: Support for a bottleneck in the 2011 Escherichia coli O104:H4 outbreak in Germany ', Proceedings of the National Academy of Sciences of the United States of America, vol. 109, no. 52, pp. 20E3629-E3630 . https://doi.org/10.1073/pnas.1209419110
- Publication Year :
- 2012
- Publisher :
- HAL CCSD, 2012.
-
Abstract
- In our paper (1), we analyzed isolates from the Escherichia coli O104:H4 outbreaks in Germany and France in May to July 2011. We concluded that, although the German outbreak was larger, the German isolates represent a clade within the greater diversity of the French outbreak. We proposed several hypotheses to explain these findings, including that the lineage leading to the German outbreak went through a narrow bottleneck that purged diversity.
- Subjects :
- 0303 health sciences
Multidisciplinary
[SDV]Life Sciences [q-bio]
education
Zoology
Outbreak
Biology
Virology
Bottleneck
language.human_language
German
03 medical and health sciences
0302 clinical medicine
Escherichia coli O104:H4
language
030212 general & internal medicine
Clade
human activities
030304 developmental biology
Subjects
Details
- Language :
- English
- ISSN :
- 00278424 and 10916490
- Database :
- OpenAIRE
- Journal :
- Proceedings of the National Academy of Sciences of the United States of America, Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2012, 109 (52), pp.E3629-30. ⟨10.1073/pnas.1209419110⟩, Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (52), pp.E3629-30. ⟨10.1073/pnas.1209419110⟩, Grad, Y H, Lipsitch, M, Griggs, A D, Haas, B J, Shea, T P, McCowan, C, Montmayeur, A, FitzGerald, M, Wortman, J R, Krogfelt, K A, Bingen, E, Weill, F-X, Tietze, E, Flieger, A, Lander, E S, Nusbaum, C, Birren, B W, Hung, D T & Hanage, W P 2012, ' Reply to Guy et al.: Support for a bottleneck in the 2011 Escherichia coli O104:H4 outbreak in Germany ', Proceedings of the National Academy of Sciences of the United States of America, vol. 109, no. 52, pp. 20E3629-E3630 . https://doi.org/10.1073/pnas.1209419110
- Accession number :
- edsair.doi.dedup.....9dc7a67072b54ce58aab5d9b2b1feda5
- Full Text :
- https://doi.org/10.1073/pnas.1209419110⟩