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On the feasibility of wireless radio frequency ablation using nanowire antennas
- Source :
- APL Materials, Vol 9, Iss 7, Pp 071103-071103-9 (2021), Apl Materials
- Publication Year :
- 2021
- Publisher :
- AIP Publishing LLC, 2021.
-
Abstract
- Radio frequency ablation (RFA) is a proven technique for eliminating cancerous or dysfunctional tissues in the body. However, the delivery of RFA electrodes to deep tissues causes damage to overlying healthy tissues, while a minimally invasive RFA technique would limit damage to targeted tissues alone. In this manuscript, we propose a wireless RFA technique relying on the absorption of radio frequencies (RFs) by gold nanowires in vivo and the deep penetration of RF into biological tissues. Upon optimizing the dimensions of the gold nanowires and the frequency of the applied RF for breast cancer and myocardium tissues, we find that heating rates in excess of 2000 K/s can be achieved with high spatial resolution in vivo, enabling short heating durations for ablation and minimizing heat diffusion to surrounding tissues. The results suggest that gold nanowires can act as “radiothermal” agents to concentrate heating within targeted tissues, negating the need to implant bulky electrodes for tissue ablation.
- Subjects :
- Materials science
Tissue ablation
business.industry
medicine.medical_treatment
Physics
QC1-999
General Engineering
Nanowire
Deep penetration
Articles
Ablation
High spatial resolution
medicine
Wireless
General Materials Science
Radio frequency
business
TP248.13-248.65
Biomedical engineering
Biotechnology
Subjects
Details
- Language :
- English
- Volume :
- 9
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- APL Materials
- Accession number :
- edsair.doi.dedup.....9de7aa97ec0e99e43f2c1ad4f5ff9a16