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DrugViz: a Cytoscape plugin for visualizing and analyzing small molecule drugs in biological networks
- Source :
- Bioinformatics. 24:2117-2118
- Publication Year :
- 2008
- Publisher :
- Oxford University Press (OUP), 2008.
-
Abstract
- Summary: DrugViz is a Cytoscape plugin that is designed to visualize and analyze small molecules within the framework of the interactome. DrugViz can import drug–target network information in an extended SIF file format to Cytoscape and display the two-dimensional (2D) structures of small molecule nodes in a unified visualization environment. It also can identify small molecule nodes by means of three different 2D structure searching methods, namely isomorphism, substructure and fingerprint-based similarity searches. After selections, users can furthermore conduct a two-side clustering analysis on drugs and targets, which allows for a detailed analysis of the active compounds in the network, and elucidate relationships between these drugs and targets. DrugViz represents a new tool for the analysis of data from chemogenomics, metabolomics and systems biology. Availability: DrugViz and data set used in Application are freely available for download at http://202.127.30.184:8080/software.html Contact: jkshen@mail.shcnc.ac.cn
- Subjects :
- Statistics and Probability
Databases, Factual
Proteome
Computer science
Systems biology
computer.software_genre
Biochemistry
Interactome
User-Computer Interface
chemistry.chemical_compound
Metabolomics
Computer Graphics
Chemogenomics
Computer Simulation
Databases, Protein
Cluster analysis
Molecular Biology
Fingerprint (computing)
Small molecule
Computer Science Applications
Visualization
Computational Mathematics
Pharmaceutical Preparations
Computational Theory and Mathematics
chemistry
Drug Design
Data mining
computer
Software
Biological network
Subjects
Details
- ISSN :
- 13674811 and 13674803
- Volume :
- 24
- Database :
- OpenAIRE
- Journal :
- Bioinformatics
- Accession number :
- edsair.doi.dedup.....9e07944454061ff0e3b675fa596058db