NF-κB inhibitors from terrestrial plants reported in 2011

This review shows that more than 40 natural products isolated from terrestrials natural sources in 2011 expressed NF-κB inhibition properties. It has to be pointed that an α,β-unsaturated ketone function was present in more than fifty percent of the reported structures, which might explain the observed bioactivity. Hence, there is still a supply of bioactive products isolated from natural sources. Briefly, this review shows the potential of natural sources as a source for the development of anti-cancer agents.