Pollen derived low molecular compounds enhance the human allergen specific immune responsein vivo

Authors :: Adam Chaker
Heidrun Behrendt
M McIntyre
Liliana Cifuentes
Murat Bas
Carsten B. Schmidt-Weber
Stefanie Gilles‐Stein
Jan Gutermuth
Arnd Petersen
Isabelle Beck
Claudia Traidl-Hoffmann
Skin function and permeability
Surgical clinical sciences
Source :: Clinical & Experimental Allergy. 46:1355-1365
Publication Year :: 2016
Publisher :: Wiley, 2016.
Abstract: BACKGROUND: Besides allergens, pollen release bioactive, low molecular weight compounds that modulate and stimulate allergic reactions. Clinical relevance of these substances hasn't been investigated to date. OBJECTIVE: To elucidate the effect of a non-allergenic, low molecular weight factors from aqueous birch pollen extracts (Bet-APE

Subjects :: medicine.medical_treatment
Mucous membrane of nose
medicine.disease_cause
Immunoglobulin E
Cell Degranulation
0302 clinical medicine
Allergen
immune system diseases
Immunology and Allergy
Betula
Medicine(all)
respiratory system
Basophils
pollen-associated lipid mediator
Pollen
Inflammation Mediators
Symptom Assessment
medicine.symptom
Nasal Provocation Tests
prick test
Immunology
Low molecular weight pollen fraction
Biology
Nasal congestion
Nasal provocation test
Immunomodulation
03 medical and health sciences
Th2 Cells
Immune system
nasal challenge
otorhinolaryngologic diseases
medicine
Humans
ddc:610
Skin Tests
rhinorrhea
Plant Extracts
Interleukin-8
Immunity
Rhinitis, Allergic, Seasonal
Allergens
respiratory tract diseases
Molecular Weight
Nasal Mucosa
030228 respiratory system
biology.protein
030215 immunology

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