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Using oral polio vaccine beyond the cold chain: A feasibility study conducted during the national immunization campaign in Mali

Authors :
Olivier Ronveaux
Ariane Halm
Simona Zipursky
Mady Kamissoko
Ndoutabe Modjirom
Umit Kartoglu
Idrissa Yalcouyé
Tenemakan Keïta
Source :
Vaccine. 28:3467-3472
Publication Year :
2010
Publisher :
Elsevier BV, 2010.

Abstract

We conducted the first systematic documentation of using oral polio vaccine (OPV) out of the cold chain during national immunization day (NID) campaigns in Mali. Using a crossover intervention design, vaccinators compared the transport of OPV in vaccine carriers with or without ice packs. Vaccine integrity was assured through monitoring vaccine vial monitor (VVM) status. Despite ambient temperatures up to 40 degrees C, none of the VVMs on any of the vials used (n=956) reached their discard point. Over 90% of vaccinators and supervisors preferred conducting NIDs without ice packs. In addition, using OPV out of the cold chain reduced vaccine wastage resulting from melting ice packs causing labels to detach from the vial.

Details

ISSN :
0264410X
Volume :
28
Database :
OpenAIRE
Journal :
Vaccine
Accession number :
edsair.doi.dedup.....9f492944facea1adeb3313c1c7969963