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Poly(ADP-ribose) polymerase: a molecular nick-sensor
- Source :
- Trends in biochemical sciences. 19(4)
- Publication Year :
- 1994
-
Abstract
- Poly(ADP-ribose) polymerase (PARP) participates in the intricate network of systems developed by the eukaryotic cell to cope with the numerous environmental and endogenous genotoxic agents. Cloning of the PARP gene has allowed the development of genetic and molecular approaches to elucidate the structure and function of this abundant and highly conserved enzyme.
- Subjects :
- chemistry.chemical_classification
Cloning
Poly Adenosine Diphosphate Ribose
Poly ADP ribose polymerase
Endogeny
Biology
Biochemistry
Structure and function
Enzyme
chemistry
biology.protein
Animals
Humans
Poly(ADP-ribose) Polymerases
Molecular Biology
Gene
Eukaryotic cell
Polymerase
Repetitive Sequences, Nucleic Acid
Subjects
Details
- ISSN :
- 09680004
- Volume :
- 19
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Trends in biochemical sciences
- Accession number :
- edsair.doi.dedup.....9f941387eb43f9d58305e2d7cc23176f