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No-Reflow after PPCI—A Predictor of Short-Term Outcomes in STEMI Patients

Authors :
Mircea Ioachim Popescu
Larisa Renata Pantea-Roșan
Marius Rus
Camelia Cristina Diaconu
Cosmin Mihai Vesa
Delia Mirela Tit
Cristiana Bustea
Vladiana Turi
Vlad Alin Pantea
Radu Dumitru Moleriu
Simona Bungau
Tapan Behl
Source :
Journal of Clinical Medicine, Volume 9, Issue 9, Journal of Clinical Medicine, Vol 9, Iss 2956, p 2956 (2020)
Publication Year :
2020
Publisher :
Multidisciplinary Digital Publishing Institute, 2020.

Abstract

The no-reflow phenomenon following primary percutaneous coronary intervention (PPCI) in acute ST-elevation myocardial infarction (STEMI) patients is a predictor of unfavorable prognosis. Patients with no-reflow have many complications during admission, and it is considered a marker of short-term mortality. The current research emphasizes the circumstances of the incidence and complications of the no-reflow phenomenon in STEMI patients, including in-hospital mortality. In this case-control study, conducted over two and a half years, there were enrolled 656 patients diagnosed with STEMI and reperfused through PPCI. Several patients (n = 96) developed an interventional type of no-reflow phenomenon. One third of the patients with a no-reflow phenomenon suffered complications during admission, and 14 succumbed. Regarding complications, the majority consisted of arrhythmias (21.68%) and cardiogenic shock (16.67%). The anterior localization of STEMI and the left anterior descending artery (LAD) as a culprit lesion were associated with the highest number of complications during hospitalization. At the same time, the time interval &gt<br />12 h from the onset of the typical symptoms of myocardial infarction (MI) until revascularization, as well as multiple stents implantations during PPCI, correlated with an increased incidence of short-term complications. The no-reflow phenomenon in patients with STEMI was associated with an unfavorable short-term prognosis.

Details

Language :
English
ISSN :
20770383
Database :
OpenAIRE
Journal :
Journal of Clinical Medicine
Accession number :
edsair.doi.dedup.....9f9b822eb4b7dc8b84219faff05044b4
Full Text :
https://doi.org/10.3390/jcm9092956