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Supplementary Table 2 from Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor Veliparib (ABT-888) in Combination with Irinotecan in Patients with Advanced Solid Tumors

Authors :
Geoffrey I. Shapiro
Ralph E. Parchment
Robert J. Kinders
Katherine Ferry-Galow
Jiuping Ji
Yiping Zhang
Allison M. Marrero
Andrew Wolanski
Tracy Bell
Dongpo Cai
Adam Bowditch
Julie L. Boerner
Lawrence Rubinstein
Alice P. Chen
James M. Cleary
Sara M. Tolaney
Jie Zhang
Mary Jo Pilat
Daryn Smith
Scott A. Boerner
Edward A. Sausville
Lance K. Heilbrun
Angelika Burger
Jing Li
Patricia M. LoRusso
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Supplementary Table 2 Pharmacokinetic parametersa of irinotecan and its main active metabolite SN-38 when irinotecan was administered as a 1.5-h intravenous infusion (100 mg/m2) alone on cycle 1 day 1 or in combination with veliparib on cycle 2 day 8

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....a0655e226af297ffb64a7958454d0e0f
Full Text :
https://doi.org/10.1158/1078-0432.22457393