Back to Search
Start Over
Additive Intraocular Pressure-Lowering Effects of a Novel Selective EP2 Receptor Agonist, Omidenepag Isopropyl, Combined with Existing Antiglaucoma Agents in Conscious Ocular Normotensive Monkeys
- Source :
- Journal of Ocular Pharmacology and Therapeutics. 37:223-229
- Publication Year :
- 2021
- Publisher :
- Mary Ann Liebert Inc, 2021.
-
Abstract
- Purpose: To investigate the intraocular pressure (IOP)-lowering effects of omidenepag isopropyl (OMDI), a potent and highly selective prostanoid EP2 receptor agonist, as a potential first-line ocul...
- Subjects :
- Male
Agonist
Intraocular pressure
Consciousness
genetic structures
Pyridines
medicine.drug_class
Administration, Topical
Prostaglandin E2 receptor
Adrenergic beta-Antagonists
Glycine
Glaucoma
Pharmacology
Tonometry, Ocular
chemistry.chemical_compound
Adrenergic alpha-2 Receptor Agonists
medicine
Animals
Pharmacology (medical)
Carbonic Anhydrase Inhibitors
Receptor
Antihypertensive Agents
Intraocular Pressure
rho-Associated Kinases
Prostanoid
Drug Synergism
Receptors, Prostaglandin E, EP2 Subtype
musculoskeletal system
Highly selective
medicine.disease
eye diseases
Macaca fascicularis
Ophthalmology
chemistry
Case-Control Studies
Pyrazoles
Drug Therapy, Combination
lipids (amino acids, peptides, and proteins)
sense organs
Ophthalmic Solutions
Isopropyl
Subjects
Details
- ISSN :
- 15577732 and 10807683
- Volume :
- 37
- Database :
- OpenAIRE
- Journal :
- Journal of Ocular Pharmacology and Therapeutics
- Accession number :
- edsair.doi.dedup.....a06ce19eed1bf26589d524e14b80da21