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Supplementary Figure 2 from Functional Genomics Uncover the Biology behind the Responsiveness of Head and Neck Squamous Cell Cancer Patients to Cetuximab

Authors :
Loris De Cecco
Silvana Canevari
Lisa Licitra
Laura D. Locati
Silvana Pilotti
Federica Perrone
Barbara Cortelazzi
Edoardo Marchesi
Marco Giannoccaro
Federica Favales
Andrea P. Sponghini
Maria Cossu Rocca
Marco Siano
Cristiana Bergamini
Paolo Bossi
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Fig S2. Technical validation using NuGEN's Ovation System. The scatter plot shows the fold change consistency of genes differentially expressed using WG-DASL and NuGEN methods. Only 6 out of the 509 DE genes were found discordant, confirming the WG-DASL patterns. Data are plotted as log2 fold change (FC) expression long/short PFS; positive log2(FC) values stand for genes up-regulated in long-PFS cases, while negative values stand for up-regulation in short-PFS cases. Statistical significance was tested through Monte Carlo test (1000 interactions) yielding p-value

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....a07c1521837d8735544ec5a5971a5bdf