Back to Search
Start Over
The glucose metabolic frame of conditions induce the overproduction of a co-culture pigment: induction mechanism of the pigment and development of a specific eutrophic-oligotrophic transition cultivation system
- Source :
- Bioprocess and biosystems engineering. 36(7)
- Publication Year :
- 2012
-
Abstract
- Induction mechanism of a potential red pigment (RPc) was investigated in the present paper. A typical competition relationship exists between Penicillium sp. HSD07B and Candida tropicalis during co-culture, and C. tropicalis converts glucose into glycerol, organic acids and other substances, resulting in a stricter glucose limitation and the secretion of RPc. Moreover, a novel eutrophic–oligotrophic transition cultivation system (E-OTCS) was developed to produce red pigment during monoculture of Penicillium sp. HSD07B. However, the monoculture pigment (RPm) is different from RPc in components, and RP3 and RP4 only occur in RPm when glycerol is supplied. In addition, the additions of glycerol and organic acids to glucose exhaustion medium can significantly improve the pigment yield. These facts not only prove the feasibility of producing RPm using E-OTCS, but also reveal that, besides glucose exhaustion, the accumulation of metabolites of glucose including glycerol and organic acids is also an important factor influencing the production of RPc.
- Subjects :
- biology
Penicillium
Bioengineering
General Medicine
Pigments, Biological
biology.organism_classification
Coculture Techniques
Candida tropicalis
Pigment
chemistry.chemical_compound
Glucose
Biochemistry
chemistry
Biotransformation
visual_art
visual_art.visual_art_medium
Glycerol
sense organs
Industrial and production engineering
Monoculture
Overproduction
Biotechnology
Subjects
Details
- ISSN :
- 16157605
- Volume :
- 36
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Bioprocess and biosystems engineering
- Accession number :
- edsair.doi.dedup.....a107dd7704ac4ea22c0c40a70bcd2c98