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Comprehensive Effects of Near-Infrared Multifunctional Liposomes on Cancer Cells
- Source :
- Molecules, Vol 25, Iss 5, p 1098 (2020), Molecules, Volume 25, Issue 5
- Publication Year :
- 2020
- Publisher :
- MDPI AG, 2020.
-
Abstract
- Multifunctional theranostic systems are a recent important development of medical research. We combined the characteristics of near-infrared luminescent quantum dots and thermosensitive magnetoliposomes to develop a multifunctional nano-diagnostic material. This system is based on near-infrared magnetic thermosensitive liposomes, which encapsulate drugs and can control drug localization and release. After incubating cancer cells with the liposomes, the state of the cells was analyzed in real time by near-infrared imaging. Cell viability was significantly inhibited by heat treatment or alternating magnetic field treatment, which thus improved the anti-cancer properties of the liposomes. In the future, by combining near-infrared imaging technology and an external high-frequency alternating magnetic field, we could not only detect cancer cells noninvasively but also conduct image-guided treatments for cancer.
- Subjects :
- Materials science
Cell Survival
Infrared Rays
theranostic
multifunctional liposomes
Pharmaceutical Science
Thermosensitive liposomes
Nanotechnology
Antineoplastic Agents
Article
Analytical Chemistry
lcsh:QD241-441
magnetothermal properties
lcsh:Organic chemistry
Neoplasms
cell imaging
Drug Discovery
Quantum Dots
medicine
Humans
Viability assay
near-infrared quantum dots
Physical and Theoretical Chemistry
Liposome
Organic Chemistry
Cancer
Hyperthermia, Induced
medicine.disease
Magnetic Fields
Chemistry (miscellaneous)
Cancer cell
Liposomes
MCF-7 Cells
Molecular Medicine
Subjects
Details
- Language :
- English
- ISSN :
- 14203049
- Volume :
- 25
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Molecules
- Accession number :
- edsair.doi.dedup.....a1b7cd2b668f873c03555b715a42c34e