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Infectious Dose of African Swine Fever Virus When Consumed Naturally in Liquid or Feed
- Source :
- Emerging Infectious Diseases, Vol 25, Iss 5, Pp 891-897 (2019)
- Publication Year :
- 2019
- Publisher :
- Centers for Disease Control and Prevention, 2019.
-
Abstract
- African swine fever virus (ASFV) is a contagious, rapidly spreading, transboundary animal disease and a major threat to pork production globally. Although plant-based feed has been identified as a potential route for virus introduction onto swine farms, little is known about the risks for ASFV transmission in feed. We aimed to determine the minimum and median infectious doses of the Georgia 2007 strain of ASFV through oral exposure during natural drinking and feeding behaviors. The minimum infectious dose of ASFV in liquid was 10(0) 50% tissue culture infectious dose (TCID(50)), compared with 10(4) TCID(50) in feed. The median infectious dose was 10(1.0) TCID(50) for liquid and 10(6.8) TCID(50) for feed. Our findings demonstrate that ASFV Georgia 2007 can easily be transmitted orally, although higher doses are required for infection in plant-based feed. These data provide important information that can be incorporated into risk models for ASFV transmission.
- Subjects :
- Microbiology (medical)
Oral dose
Georgia
Epidemiology
Swine
animal diseases
030231 tropical medicine
lcsh:Medicine
Biology
African swine fever virus
Virus
lcsh:Infectious and parasitic diseases
03 medical and health sciences
0302 clinical medicine
median infectious dose
Food microbiology
Animals
oral dose
lcsh:RC109-216
030212 general & internal medicine
African Swine Fever
minimum infectious dose
Virulence
Transmission (medicine)
Infectious dose
Research
Animal disease
feed
lcsh:R
biology.organism_classification
Virology
Animal Feed
Infectious Diseases
Food Microbiology
ASFV
Subjects
Details
- Language :
- English
- ISSN :
- 10806059 and 10806040
- Volume :
- 25
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Emerging Infectious Diseases
- Accession number :
- edsair.doi.dedup.....a1c4f0a1e985abb9bf36a8e88fc511a8