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Diagnosis and Management of Acute Coronary Syndrome: What is New and Why? Insight From the 2020 European Society of Cardiology Guidelines
- Source :
- Journal of Clinical Medicine, Journal of Clinical Medicine, Vol 9, Iss 3474, p 3474 (2020), Journal of Clinical Medicine, MDPI, 2020, 9 (11), pp.3474. ⟨10.3390/jcm9113474⟩, Journal of Clinical Medicine, 2020, 9 (11), pp.3474. ⟨10.3390/jcm9113474⟩
- Publication Year :
- 2020
- Publisher :
- MDPI, 2020.
-
Abstract
- International audience; The management of acute coronary syndrome (ACS) has been at the center of an impressive amount of research leading to a significant improvement in outcomes over the last 50 years. The 2020 European Society of Cardiology (ESC) Guidelines for the management of patients presenting without persistent ST-segment elevation myocardial infarction have incorporated the most recent breakthroughs and updates from large randomized controlled trials (RCT) on the diagnosis and management of this disease. The purpose of the present review is to describe the main novelties and the rationale behind these recommendations. Hence, we describe the accumulating evidence against P2Y12 receptors inhibitors pretreatment prior to coronary angiography, the preference for prasugrel as leading P2Y12 inhibitors in the setting of ACS, and the numerous available antithrombotic regimens based on various durations of dual or triple antithrombotic therapy, according to the patient ischemic and bleeding risk profiles. We also detail the recently implemented 0 h/1 h and 0 h/2 h rule in, rule out algorithms and the growing role of computed coronary tomography angiography to rule out ACS in patients at low-to-moderate risk.
- Subjects :
- Acute coronary syndrome
medicine.medical_specialty
Prasugrel
medicine.medical_treatment
[SDV]Life Sciences [q-bio]
lcsh:Medicine
Review
030204 cardiovascular system & hematology
antiplatelet
law.invention
acute coronary syndrome
03 medical and health sciences
0302 clinical medicine
Randomized controlled trial
law
Internal medicine
Antithrombotic
medicine
030212 general & internal medicine
Myocardial infarction
oral anticoagulation
Management of acute coronary syndrome
medicine.diagnostic_test
business.industry
lcsh:R
percutaneous coronary intervention
Percutaneous coronary intervention
General Medicine
medicine.disease
3. Good health
[SDV] Life Sciences [q-bio]
Angiography
Cardiology
business
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 20770383
- Volume :
- 9
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Medicine
- Accession number :
- edsair.doi.dedup.....a1fd1999ac57529437f780be89de7361