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Trend of Olfactory and Gustatory Dysfunction in COVID-19 Patients in a Quarantine Facility
- Source :
- Journal of Korean Medical Science
- Publication Year :
- 2020
- Publisher :
- The Korean Academy of Medical Sciences, 2020.
-
Abstract
- Background Olfactory and gustatory dysfunction has been reported as characteristic symptoms of coronavirus disease 2019 (COVID-19). This study evaluated olfactory and gustatory dysfunction in mild COVID-19 patients using validated assessment methods. Methods A prospective surveillance study was conducted for mild COVID-19 patients who were isolated at the Gyeonggi International Living and Treatment Support Center (LTSC), Korea. Olfactory function was assessed using the Korean version of the Questionnaire of Olfactory Disorders (QOD) and Cross-Cultural Smell Identification Test (CC-SIT). Gustatory function was assessed using an 11-point Likert scale and 6-n-propylthiouracil, phenylthiocarbamide, and control strips. All patients underwent nasal and oral cavity endoscopic examination. Results Of the 62 patients at the LTSC, 15 patients (24.2%) complained of olfactory or gustatory dysfunction on admission. Four of 10 patients who underwent functional evaluation did not have general symptoms and 2 were asymptomatic. The mean short version of QOD-negative statements and QOD-visual analogue scale scores were 13 ± 6 and 4.7 ± 3.6, respectively. The mean CC-SIT score was 8 ± 2. No patients showed anatomical abnormalities associated with olfactory dysfunction on endoscopic examination. The mean Likert scale score for function was 8 ± 2, and there were no abnormal lesions in the oral cavity of any patient. Conclusions The prevalence of olfactory and gustatory dysfunction was 24.2% in mild COVID-19 patients. All patients had hyposmia due to sensorineural olfactory dysfunction, which was confirmed using validated olfactory and gustatory evaluation methods and endoscopic examination. Olfactory and gustatory dysfunction may be characteristic indicators of mild COVID-19.<br />Graphical Abstract
- Subjects :
- Olfactory system
Adult
Male
medicine.medical_specialty
Pneumonia, Viral
Asymptomatic
Gastroenterology
03 medical and health sciences
chemistry.chemical_compound
Olfaction Disorders
Taste Disorders
Betacoronavirus
Young Adult
0302 clinical medicine
Hyposmia
Internal medicine
Surveys and Questionnaires
Republic of Korea
medicine
Humans
030212 general & internal medicine
Prospective Studies
Young adult
Prospective cohort study
Pandemics
Phenylthiocarbamide
Cultural Characteristics
medicine.diagnostic_test
business.industry
SARS-CoV-2
COVID-19
Reproducibility of Results
Endoscopy
General Medicine
Infectious Diseases, Microbiology & Parasitology
Middle Aged
Smell
Taste disorder
chemistry
Quarantine
Original Article
Female
medicine.symptom
Symptom Assessment
business
Coronavirus Infections
Subjects
Details
- Language :
- English
- ISSN :
- 15986357 and 10118934
- Volume :
- 35
- Issue :
- 41
- Database :
- OpenAIRE
- Journal :
- Journal of Korean Medical Science
- Accession number :
- edsair.doi.dedup.....a2b4b306e5b34a298d34a15c254429cf