Back to Search Start Over

Use and Discontinuation of Insulin Treatment Among Adults Aged 75 to 79 Years With Type 2 Diabetes

Authors :
Kasia J. Lipska
Pranita Mishra
Neda Laiteerapong
Andrew J. Karter
Elbert S. Huang
Anjali Gopalan
Richard W. Grant
Jonathan Z. Weiner
Source :
JAMA Intern Med
Publication Year :
2019
Publisher :
American Medical Association (AMA), 2019.

Abstract

IMPORTANCE: Among older individuals with type 2 diabetes, those with poor health have greater risk and derive less benefit from tight glycemic control with insulin. OBJECTIVE: To examine whether insulin treatment is used less frequently and discontinued more often among older individuals with poor health compared with those in good health. DESIGN, SETTING, AND PARTICIPANTS: This longitudinal cohort study included 21 531 individuals with type 2 diabetes followed for up to 4 years starting at age 75 years. Electronic health record data from the Kaiser Permanente Northern California Diabetes Registry was collected to characterize insulin treatment and glycemic control over time. Data were collected from January 1, 2009, through December 31, 2017, and analyzed from February 2, 2018, through June 30, 2019. EXPOSURES: Health status was defined as good (2 comorbidities or 2 comorbidities and no self-reported weekly exercise), or poor (having end-stage pulmonary, cardiac, or renal disease; diagnosis of dementia; or metastatic cancer). MAIN OUTCOMES AND MEASURES: Insulin use prevalence at age 75 years and discontinuation among insulin users over the next 4 years (or 6 months prior to death if

Details

ISSN :
21686106
Volume :
179
Database :
OpenAIRE
Journal :
JAMA Internal Medicine
Accession number :
edsair.doi.dedup.....a2c31b7e7d85239741222a3039e7ff6d
Full Text :
https://doi.org/10.1001/jamainternmed.2019.3759