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Use and Discontinuation of Insulin Treatment Among Adults Aged 75 to 79 Years With Type 2 Diabetes
- Source :
- JAMA Intern Med
- Publication Year :
- 2019
- Publisher :
- American Medical Association (AMA), 2019.
-
Abstract
- IMPORTANCE: Among older individuals with type 2 diabetes, those with poor health have greater risk and derive less benefit from tight glycemic control with insulin. OBJECTIVE: To examine whether insulin treatment is used less frequently and discontinued more often among older individuals with poor health compared with those in good health. DESIGN, SETTING, AND PARTICIPANTS: This longitudinal cohort study included 21 531 individuals with type 2 diabetes followed for up to 4 years starting at age 75 years. Electronic health record data from the Kaiser Permanente Northern California Diabetes Registry was collected to characterize insulin treatment and glycemic control over time. Data were collected from January 1, 2009, through December 31, 2017, and analyzed from February 2, 2018, through June 30, 2019. EXPOSURES: Health status was defined as good (2 comorbidities or 2 comorbidities and no self-reported weekly exercise), or poor (having end-stage pulmonary, cardiac, or renal disease; diagnosis of dementia; or metastatic cancer). MAIN OUTCOMES AND MEASURES: Insulin use prevalence at age 75 years and discontinuation among insulin users over the next 4 years (or 6 months prior to death if
- Subjects :
- Blood Glucose
Male
Pediatrics
medicine.medical_specialty
medicine.medical_treatment
Disease
Type 2 diabetes
01 natural sciences
03 medical and health sciences
0302 clinical medicine
Diabetes mellitus
Internal Medicine
medicine
Humans
Hypoglycemic Agents
Insulin
Dementia
Longitudinal Studies
030212 general & internal medicine
0101 mathematics
Aged
Original Investigation
Glycemic
Glycated Hemoglobin
business.industry
010102 general mathematics
medicine.disease
Discontinuation
Diabetes Mellitus, Type 2
Withholding Treatment
Relative risk
Female
business
Subjects
Details
- ISSN :
- 21686106
- Volume :
- 179
- Database :
- OpenAIRE
- Journal :
- JAMA Internal Medicine
- Accession number :
- edsair.doi.dedup.....a2c31b7e7d85239741222a3039e7ff6d
- Full Text :
- https://doi.org/10.1001/jamainternmed.2019.3759