Back to Search
Start Over
Impact of haemodynamic SonR sensor on monitoring of left ventricular function in patients undergoing cardiac resynchronization therapy
- Source :
- Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 19(10)
- Publication Year :
- 2016
-
Abstract
- Aims The haemodynamic SonR sensor is able to measure myocardial contractility. The isometric effort is useful in quantifying left ventricular (LV) performance. We investigated the amplitude changes in SonR signal over time and during static exercise according to the recovery of the left ventricle. Methods and results Twenty five patients [18 male, 70 ± 8 years, LV ejection fraction (LVEF) 29 ± 5%, in sinus rhythm] underwent biventricular SonR implantable cardioverter defibrillator implant. After procedure and at 6 months, each patient underwent detection of SonR signal and continuous measurement of blood pressure, at rest and during isometric effort. During evaluation at baseline device was programmed in VVI at 40 bpm while in DDD at 60 bpm at follow-up. At 6 months, LV reverse remodelling was investigated. Cardiac resynchronization therapy patients were considered responders when an absolute improvement in LV ejection fraction ≥ 5% occurred. At 6 months, 14 (56%) patients were responders and 11 (44%) non-responders (mean LVEF 40 ± 10% vs. 27 ± 6%, respectively). In responders, SonR value did not significantly change at follow-up compared to baseline ( P = 0.894). At follow-up, SonR value was not significantly different between two groups ( P = 0.651). SonR signal significantly increased during isometric effort in responders ( P = 0.002) while it slightly decreased in non-responders at follow-up ( P = 0.572). No differences were observed in response to isometric effort between two groups at baseline ( P = 0.182, P = 0.069, respectively). Conclusions The absolute SonR amplitude provides limited information on the status of LV performance. The variation in SonR signal during static exercise is more likely to identify responders at follow-up.
- Subjects :
- Male
Time Factors
020205 medical informatics
medicine.medical_treatment
Blood Pressure
02 engineering and technology
Isometric exercise
030204 cardiovascular system & hematology
Ventricular Function, Left
Cardiac Resynchronization Therapy
Ventricular Dysfunction, Left
0302 clinical medicine
Heart Rate
0202 electrical engineering, electronic engineering, information engineering
Telemetry
Sinus rhythm
Prospective Studies
Ejection fraction
Ventricular Remodeling
Signal Processing, Computer-Assisted
Stroke volume
Equipment Design
Middle Aged
Implantable cardioverter-defibrillator
Defibrillators, Implantable
Treatment Outcome
Heart Function Tests
Cardiology
Female
Cardiology and Cardiovascular Medicine
medicine.medical_specialty
Transducers
Cardiac resynchronization therapy
Electric Countershock
03 medical and health sciences
Predictive Value of Tests
Physiology (medical)
Internal medicine
Isometric Contraction
Heart rate
medicine
Humans
Cardiac Resynchronization Therapy Devices
Aged
Heart Failure
business.industry
Hemodynamics
Stroke Volume
Recovery of Function
medicine.disease
Myocardial Contraction
Heart failure
Exercise Test
business
Subjects
Details
- ISSN :
- 15322092
- Volume :
- 19
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
- Accession number :
- edsair.doi.dedup.....a4530204890b611319fec791697f31e9