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Changing trends in mortality among solid organ transplant recipients hospitalized for COVID‐19 during the course of the pandemic

Authors :
Heldman, M. R.
Kates, O. S.
Safa, K.
Kotton, C. N.
Georgia, S. J.
Steinbrink, J. M.
Alexander, B. D.
Hemmersbach-Miller, M.
Blumberg, E. A.
Multani, A.
Haydel, B.
La Hoz, R. M.
Moni, L.
Condor, Y.
Flores, S.
Munoz, C. G.
Guitierrez, J.
Diaz, E. I.
Diaz, D.
Vianna, R.
Guerra, G.
Loebe, M.
Rakita, R. M.
Malinis, M.
Azar, M. M.
Hemmige, V.
Mccort, M. E.
Chaudhry, Z. S.
Singh, P. P.
Hughes Kramer, K.
Velioglu, A.
Yabu, J. M.
Morillis, J. A.
Mehta, S. A.
Tanna, S. D.
Ison, M. G.
Derenge, A. C.
van Duin, D.
Maximin, A.
Gilbert, C.
Goldman, J. D.
Lease, E. D.
Fisher, C. E.
Limaye, A. P.
De la Cruz, O.
Besharatian, B. D.
Crespo, M.
Tomic, R.
Sehgal, S.
Weisshaar, D.
Girgis, R.
Lawrence, C.
Nelson, J.
Bennett, W.
Leandro, J.
Sait, A.
Rumore, A.
West, P.
Jeng, A.
Bajrovic, V.
Bilgili, E. P.
Anderson-Haag, T.
Nastase, A.
Badami, A.
Alvarez-Garcia, J.
Bowman-Anger, L.
Julien, L.
Ortiz-Bautista, C.
Friedman-Morocco, R.
Gajurel, K.
Cahuayme-Zuniga, L.
Wakefield, M.
Fung, M.
Theodoropoulos, N.
Chuang, S. T.
Bhandaram, S.
Veroux, M.
Chopra, B.
Florescu, D.
Witteck, D.
Ripley, K.
Saharia, K.
Akkina, S.
Mccarty, T. P.
Webb, A.
Arya, A.
Vedula, G.
El-Amm, J. -M.
Katherine Dokus, M.
Narayanan, A.
Cilene Leon Bueno de Camargo, P.
Ouseph, R.
Breuckner, A.
Luk, A.
Aujayeb, A.
Ganger, D.
Keith, D. S.
Meloni, F.
Haidar, G.
Zapernick, L.
Moraels, M.
Goyal, N.
Sharma, T.
Malhotra, U.
Kuo, A.
Rossi, A. P.
Edwards, A.
Keller, B.
Beneri, C.
Derringer, D.
Dominguez, E.
Carlson, E.
Hashim, F.
Murad, H.
Wilkens, H.
Neumann, H.
Gani, I.
Kahwaji, J.
Popoola, J.
Michaels, M.
Jakharia, N.
Puing, A.
Motallebzadeh, R.
Velagapudi, R.
Kapoor, R.
Allam, S.
Silveira, F.
Vora, S.
Kelly, U. M.
Reddy, U.
Dharnidharka, V.
Wadei, H.
Zurabi, L.
Heldman, Madeleine R.
Kates, Olivia S.
Safa, Kassem
Kotton, Camille N.
Georgia, Sarah J.
Steinbrink, Julie M.
Alexander, Barbara D.
Hemmersbach-Miller, Marion
Blumberg, Emily A.
Multani, Ashrit
Haydel, Brandy
La Hoz, Ricardo M.
Moni, Lisset
Condor, Yesabeli
Flores, Sandra
Munoz, Carlos G.
Guitierrez, Juan
Diaz, Esther I.
Diaz, Daniela
Vianna, Rodrigo
Guerra, Giselle
Loebe, Matthias
Rakita, Robert M.
Malinis, Maricar
Azar, Marwan M.
Hemmige, Vagish
McCort, Margaret E.
Chaudhry, Zohra S.
Singh, Pooja P.
Hughes Kramer, Kailey
Velioglu, Arzu
Yabu, Julie M.
Morillis, Jose A.
Mehta, Sapna A.
Tanna, Sajal D.
Ison, Michael G.
Derenge, Ariella C.
van Duin, David
Maximin, Adrienne
Gilbert, Carlene
Goldman, Jason D.
Lease, Erika D.
Fisher, Cynthia E.
Limaye, Ajit P.
Source :
American Journal of Transplantation, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, vol 22, iss 1, Am J Transplant
Publication Year :
2021
Publisher :
John Wiley and Sons Inc., 2021.

Abstract

Mortality among patients hospitalized for COVID-19 has declined over the course of the pandemic. Mortality trends specifically in solid organ transplant recipients (SOTR) are unknown. Using data from a multicenter registry of SOTR hospitalized for COVID-19, we compared 28-day mortality between early 2020 (March 1, 2020-June 19, 2020) and late 2020 (June 20, 2020-December 31, 2020). Multivariable logistic regression was used to assess comorbidity-adjusted mortality. Time period of diagnosis was available for 1435/1616 (88.8%) SOTR and 971/1435 (67.7%) were hospitalized: 571/753 (75.8%) in early 2020 and 402/682 (58.9%) in late 2020 (p&nbsp

Subjects

Subjects :
medicine.medical_specialty
infection and infectious agents
infection and infectious agents - viral
Coronavirus disease 2019 (COVID-19)
infectious disease
Population
Logistic regression
Brief Communication
clinical research/practice
Medical and Health Sciences
Article
infection and infectious agents ‐ viral
quality of care
Internal medicine
Pandemic
quality of care/care delivery
care delivery
Immunology and Allergy
Medicine
Humans
Pharmacology (medical)
organ transplantation in general
Mortality trends
education
Pandemics
Dexamethasone
UW COVID-19 SOT Study Team
education.field_of_study
Transplantation
business.industry
SARS-CoV-2
COVID-19
Hydroxychloroquine
Organ Transplantation
Transplant Recipients
practice
Good Health and Well Being
clinical research
Surgery
business
Solid organ transplantation
Brief Communications
medicine.drug
viral

Details

Language :
English
ISSN :
16006143 and 16006135
Database :
OpenAIRE
Journal :
American Journal of Transplantation
Accession number :
edsair.doi.dedup.....a4c2a2f52f426488cc785483ebd75571

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Authors Abstract Subjects Details