Targeting YAP-dependent MDSC infiltration impairs tumor progression

Authors :: Xin Lu
Y. Alan Wang
Lynda Chin
Christopher J. Logothetis
Elsa M. Li Ning Tapia
Zhuangna Fang
Pingping Hou
Baoli Hu
Trang N. Tieu
Shan Jiang
Kun Zhao
Xiaoying Shang
Guocan Wang
Chia Chin Wu
Ramakrishna Konaparthi
Sujun Hua
Sunada Khadka
Timothy P. Heffernan
Vandhana Ramamoorthy
Ronald A. DePinho
Avnish Kapoor
Pingna Deng
Mark J. McArthur
Zhenglin Guo
Di Zhao
Neelay Bhaskar Patel
Qing Chang
Patricia Troncoso
Prasenjit Dey
Jianhua Zhang
Source :: Journal for Immunotherapy of Cancer
Publication Year :: 2015
Publisher :: BMJ, 2015.
Abstract: Meeting abstracts Myeloid-derived suppressor cells (MDSCs) represent a phenotypically heterogeneous population of immature myeloid cells that play a tumor-promoting role by maintaining a state of immunological anergy and tolerance. Similar to other solid tumor types, Prostate cancer (PCa) is

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