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Direction‐ and rate‐dependent fractionation during atrial fibrillation persistence: Unmasking cardiac anisotropy?
- Source :
- Journal of Cardiovascular Electrophysiology, Journal of Cardiovascular Electrophysiology, 31(8), 2206-2209. Wiley-Blackwell Publishing Ltd
- Publication Year :
- 2020
- Publisher :
- Wiley, 2020.
-
Abstract
- This human case is the first to illustrate morphological manifestations of direction‐ and rate‐dependent anisotropic conduction in high‐resolution unipolar atrial potentials. Premature impulses induced low‐amplitude, fractionated extracellular potentials with exceptionally prolonged durations in a 76‐year old longstanding persistent patient with atrial fibrillation (AF), demonstrating direction‐dependency of anisotropic conduction. An increased pacing frequency induced presence of similar fractionated potentials, reflecting rate‐dependent anisotropy and inhomogeneous, slow conduction. Pacing with different rates and from different sites could aid in identifying nonuniform anisotropic tissue and thus the substrate of AF.
- Subjects :
- Special Section: Cast‐af 2019
Case Reports
anisotropy
030204 cardiovascular system & hematology
surgical ablation
03 medical and health sciences
0302 clinical medicine
Nuclear magnetic resonance
Physiology (medical)
Medicine
atrial fibrillation
fractionation
030212 general & internal medicine
Rate dependency
Anisotropy
Anisotropic conduction
rate‐dependency
business.industry
Rate dependent
Atrial fibrillation
Thermal conduction
medicine.disease
direction‐dependency
Cardiology and Cardiovascular Medicine
business
Persistence (discontinuity)
Surgical ablation
Subjects
Details
- ISSN :
- 15408167 and 10453873
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- Journal of Cardiovascular Electrophysiology
- Accession number :
- edsair.doi.dedup.....a5631850aa03d5e6cc618ad8fecd18b7