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An implantable MEMS drug delivery device for rapid delivery in ambulatory emergency care

Authors :
Hong Linh Ho Duc
Michael J. Cima
Noel M. Elman
Source :
Biomedical microdevices. 11(3)
Publication Year :
2009

Abstract

We introduce the first implantable drug delivery system based on MEMS (Micro-Electro-Mechanical-Systems) technology specifically designed as a platform for treatment in ambulatory emergency care. The device is named IRD(3) (implantable rapid drug delivery device) and allows rapid delivery of drugs. Vasopressin was used as a model drug for in vitro tests as it is a commonly used drug for cardiac resuscitation. Experimental results reveal that the IRD(3) provides an effective method for rapid delivery without significant drug degradation. Several medical uses and delivery modalities for IRD(3) are proposed.

Details

ISSN :
15728781
Volume :
11
Issue :
3
Database :
OpenAIRE
Journal :
Biomedical microdevices
Accession number :
edsair.doi.dedup.....a5a840bdb467fdb110f95269cf1937e8