Back to Search
Start Over
Relative and Absolute Structure Assignments of Alkenes Using Crystalline Osmate Derivatives for X-ray Analysis
- Source :
- Organic Letters. 21:10125-10129
- Publication Year :
- 2019
- Publisher :
- American Chemical Society (ACS), 2019.
-
Abstract
- Osmium tetroxide and TMEDA form stable crystalline adducts with alkenes. The structure of liquid alkenes can be determined through X-ray analysis of these derivatives. Osmium, a heavy atom, facilitates the crystallographic analysis and the determination of the absolute configuration using common Mo X-ray sources. The utility of this method for assigning structures and absolute configurations was demonstrated on a number of unsaturated substrates that include simple alkenes, enones, enol ethers, and silyl enol ethers.
- Subjects :
- Silylation
010405 organic chemistry
Chemistry
Organic Chemistry
Absolute configuration
chemistry.chemical_element
010402 general chemistry
01 natural sciences
Biochemistry
Enol
0104 chemical sciences
Adduct
Absolute structure
chemistry.chemical_compound
Crystallography
Osmium tetroxide
Atom
Osmium
Physical and Theoretical Chemistry
Subjects
Details
- ISSN :
- 15237052 and 15237060
- Volume :
- 21
- Database :
- OpenAIRE
- Journal :
- Organic Letters
- Accession number :
- edsair.doi.dedup.....a5b6c271b8b3a77fdbdcf7392beff678