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The role and uses of antibodies in COVID-19 infections: a living review

Authors :
Scourfield, D Oliver
Reed, Sophie G
Quastel, Max
Alderson, Jennifer
Bart, Valentina M T
Teijeira Crespo, Alicia
Jones, Ruth
Pring, Ellie
Richter, Felix Clemens
Ahern, David J
Almuttaqi, Hannah
Alonzi, Dominic S
Alrubayyi, Aljawharah
Alsaleh, Ghada
Batchelor, Vicky
Bayliss, Rebecca
Berthold, Dorothée L
Bezbradica, Jelena S
Bharuchq, Tehmina
Borrmann, Helene
Borsa, Mariana
Borst, Rowie
Brun, Juliane
Burnell, Stephanie E A
Capitani, Lorenzo
Cavounidis, Athena
Chapman, Lucy
Chauveau, Anne
Cifuentes, Liliana
Codd, Amy Susan
Compeer, Ewoud Bernardus
Coveney, Clarissa
Cross, Amy
Danielli, Sara
Davies, Luke C
Dendrou, Calliope A
Dimonte, Sandra
Peter Durairaj, Ruban Rex
Dustin, Lynn B
Dyer, Arthur
Fielding, Ceri
Fischer, Fabian
Gallimore, Awen
Galloway, Sarah
Gammage, Anís
Gea-Mallorquí, Ester
Godkin, Andrew
Hanna, Stephanie Jean
Heuberger, Cornelia
Hulin-Curtis, Sarah
Issa, Fadi
Jones, Emma
Ladell, Kristin
Lauder, Sarah N
Liddiard, Kate
Ligoxygakis, Petros
Lu, Fangfang
MacLachlan, Bruce
Maleki-Toyserkani, Shayda
Mann, Elizabeth H
Marzeda, Anna M
James Matthews, Reginald
Mazet, Julie M
Milicic, Anita
Mitchell, Emma
Moon, Owen
Nguyen, Van Dien
OHanlon, Miriam
Eléonore Pavillet, Clara
Peppa, Dimitra
Pires, Ana
Pring, Eleanor
Reed, Sophie
Rehwinkel, Jan
Richmond, Niamh
Robinson, Alice J B
Rodrigues, Patrícia R S
Sabberwal, Pragati
Sami, Arvind
Peres, Raphael Sanches
Sattentau, Quentin
Schonfeldova, Barbora
Scourfield, David Oliver
Selvakumar, Tharini A
Shepherd, Freya R
Shorten, Cariad
Simon, Anna Katharina
Smith, Adrian L
Crespo, Alicia Teijeira
Tellier, Michael
Thornton, Emily
Uhl, Lion F K
van Grinsven, Erinke
Wann, Angus K T
Williams, Richard
Wilson, Joseph D
Zhou, Dingxi
Zhu, Zihan
Consortium, Oxford-Cardiff COVID-19 Literature
Source :
Oxford Open Immunology
Publication Year :
2021
Publisher :
Oxford University Press (OUP), 2021.

Abstract

Coronavirus disease 2019 has generated a rapidly evolving field of research, with the global scientific community striving for solutions to the current pandemic. Characterizing humoral responses towards SARS-CoV-2, as well as closely related strains, will help determine whether antibodies are central to infection control, and aid the design of therapeutics and vaccine candidates. This review outlines the major aspects of SARS-CoV-2-specific antibody research to date, with a focus on the various prophylactic and therapeutic uses of antibodies to alleviate disease in addition to the potential of cross-reactive therapies and the implications of long-term immunity.

Details

ISSN :
26336960
Volume :
2
Database :
OpenAIRE
Journal :
Oxford Open Immunology
Accession number :
edsair.doi.dedup.....a6ab5989b4bb65194453fd61673c6ece