Ancestry-based stratified analysis of Immunochip data identifies novel associations with celiac disease

Authors :: Iñaki Irastorza
Jose Ramon Bilbao
Koldo Garcia-Etxebarria
Maria Legarda
Amaia Jauregi-Miguel
Irati Romero-Garmendia
Leticia Plaza-Izurieta
Source :: European Journal of Human Genetics. 24:1831-1834
Publication Year :: 2016
Publisher :: Springer Science and Business Media LLC, 2016.
Abstract: To identify candidate genes in celiac disease (CD), we reanalyzed the whole Immunochip CD cohort using a different approach that clusters individuals based on immunoancestry prior to disease association analysis, rather than by geographical origin. We detected 636 new associated SNPs (P

Full Text Access

Tools