The glucose tolerance test and the response of intraocular pressure to topical corticosteroids

Glucose tolerance tests were performed on 100 patients classified as high (gg) intraocular pressure responders (> 31 mm. Hg) to topical dexamethasone and compared with 100 matched patients classified as low (nn and ng) intraocular pressure responders. The sum of plasma glucose values at 0, 1, 2, and 3 hours was distributed in approximately Gaussian fashion for the poor intraocular pressure responders (mean 450 ± 70 (σ) mg./100 ml. Plasma glucose sums of 600 mg./100 ml. or more were found in 21 per cent of the gg patients but in only 3 per cent of the nnng group.