Antifungal activity of flocculosin, a novel glycolipid isolated from Pseudozyma flocculosa

Flocculosin, a glycolipid isolated from the yeast-like fungus Pseudozyma flocculosa , was investigated for in vitro antifungal activity. The compound displayed antifungal properties against several pathogenic yeasts. Synergistic activity was observed between flocculosin and amphotericin B, and no significant cytotoxicity was demonstrated when tested against human cell lines.