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The human body at cellular resolution: the NIH Human Biomolecular Atlas Program

Authors :
William J. Greenleaf
Sarah A. Teichmann
Margaret Vella
Ajay Pillai
Aviv Regev
Ananda L. Roy
Kristin E. Burnum-Johnson
Cole Trapnell
Yiing Lin
Marda Jorgensen
Gloria S. Pryhuber
Leslie Gaffney
Ken S. Lau
Kimberly Robasky
Jeffrey M. Spraggins
Chuck McCallum
Stavros Michailidis
Randy Heiland
Orit Rozenblatt-Rosen
Allyson Ricarte
Xin bSun
Kevin J. Otto
Amir Bahmani
Zorina S. Galis
James S. Hagood
Monica Nagendran
Gökcen Eraslan
Robin M. Scibek
Jocelyn Y. Kishi
Jay Mulye
Maria Keays
Griffin M. Weber
Caltech-UW Tmc
Charles Ansong
Nicholas A. Nystrom
Vishal G. Venkataraaman
Vladimir Yu. Kiselev
Ucsd Tmc
Ellen M. Quardokus
Tushar bDesai
Bruce Herr
Engagement Component
James E. Anderson
Shin Lin
Lisel Record
Peter V. Kharchenko
Robert F. dMurphy
Stanford-WashU Tmc
Yu Wang
Jian Ma
Sergio Maffioletti
Sarah Black
Matthew Ruffalo
Salvatore Sechi
John C. Marioni
Ziv Bar-Joseph
Richard M. Caprioli
Stanford Ttd
Garry P. Nolan
Marishka Brown
Elizabeth L. Wilder
Maigan A. Brusko
Peter Chou
Tommaso Biancalani
Christian Martijn Schuerch
Julia Laskin
Richard Conroy
Jonathan C. Silverstein
Paula M. Mabee
Dena Procaccini
Pehr B. Harbury
Michael Snyder
Pothur Srinivas
Jennifer Rood
Dana Jackson
Sanjay Jain
Katy Börner
Visualization HuBMAP Integration
William E. Shirey
Sinem K. Saka
James P. Sluka
Agnes B. Fogo
Isabel Goldaracena
Sushma A. Akoju
Raymond C. Harris
Rahul Satija
Sylvia K. Plevritis
Tim Stuart
Shila Ghazanfar
Peng Yin
Harvard Ttd
Aaron M. Horning
Ed Esplin
Amanda Posgai
Michael J. Clare-Salzler
Raf Van de Plas
Aaron Pawlyk
Guo-Cheng Yuan
Benedict aten
DongHye Ye
Hayan Lee
Eyal Fisher
Jay Shendure
Long Cai
Danielle cGutierrez
Carl Kingsford
Ruben Dries
Sara Ahadi
Paul D. Piehowski
Bernd bBodenmiller
Purdue Ttd
Stephanie A. Nevins
Philip D. Blood
Andrew Butler
W. Christopher Lenhardt
Ying Zhu
Alexander J. Ropelewski
Harry S. Nick
Nathan Heath Patterson
Elizabeth K. Neumann
Anna Hupalowska
Samuel H. Friedman
Clive hWasserfall
Qian Zhu
Mark P. deCaestecker
Leonard E. Cross
Mark A. Atkinson
Paul Macklin
Todd M. Brusko
Eeshit Dhaval Vaishnav
Nils Gehlenborg
Kun Zhang
Source :
Nature
Publication Year :
2019
Publisher :
Nature Publishing Group UK, 2019.

Abstract

Transformative technologies are enabling the construction of three-dimensional maps of tissues with unprecedented spatial and molecular resolution. Over the next seven years, the NIH Common Fund Human Biomolecular Atlas Program (HuBMAP) intends to develop a widely accessible framework for comprehensively mapping the human body at single-cell resolution by supporting technology development, data acquisition, and detailed spatial mapping. HuBMAP will integrate its efforts with other funding agencies, programs, consortia, and the biomedical research community at large towards the shared vision of a comprehensive, accessible three-dimensional molecular and cellular atlas of the human body, in health and under various disease conditions.<br />HuBMAP supports technology development, data acquisition, and spatial analyses to generate comprehensive molecular and cellular three-dimensional tissue maps.

Details

Language :
English
ISSN :
14764687 and 00280836
Volume :
574
Issue :
7777
Database :
OpenAIRE
Journal :
Nature
Accession number :
edsair.doi.dedup.....a760adbbc42a3cb40fdfb6a51c3f81aa