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Global initiative for congenital toxoplasmosis: an observational and international comparative clinical analysis

Authors :
Amina Berraho
Manoradhan Murugesan
Jorge Enrique Gómez-Marín
El Bachir Adlaoui
Fred Quinn
Azeddine Ibrahimi
Bouchra El Mansouri
Majda Laboudi
A. Barkat
Fouad Seghrouchni
Rima McLeod
Pauline Levigne
François Peyron
Mohamed Rhajaoui
Joseph D. Lykins
Kamal El Bissati
Source :
Emerging Microbes and Infections, Vol 7, Iss 1, Pp 1-14 (2018)
Publication Year :
2018
Publisher :
Informa UK Limited, 2018.

Abstract

Globally, congenital toxoplasmosis remains a significant cause of morbidity and mortality, and outbreaks of infection with T. gondii represent a significant, emerging public health burden, especially in the developing world. This parasite is a threat to public health. Disease often is not recognized and is inadequately managed. Herein, we analyze the status of congenital toxoplasmosis in Morocco, Colombia, the United States, and France. We identify the unique challenges faced by each nation in the implementation of optimal approaches to congenital toxoplasmosis as a public health problem. We suggest that developed and developing countries use a multipronged approach, modeling their public health management protocols after those in France. We conclude that education, screening, appropriate treatment, and the development of novel modalities will be required to intervene successfully in caring for individuals with this infection. Gestational screening has been demonstrated to be cost-effective, morbidity-sparing, and life-saving. Recognition of the value and promise of public health interventions to prevent human suffering from this emerging infection will facilitate better patient and societal outcomes.

Details

ISSN :
22221751
Volume :
7
Database :
OpenAIRE
Journal :
Emerging Microbes & Infections
Accession number :
edsair.doi.dedup.....a787f516d142ae8556eee280bdf5d6cf
Full Text :
https://doi.org/10.1038/s41426-018-0164-4