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Clinical implementation of a wide-field electron arc technique with a scatterer for widespread Kaposi’s sarcoma in the distal extremities
- Source :
- Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020), Scientific Reports
- Publication Year :
- 2020
- Publisher :
- Nature Publishing Group, 2020.
-
Abstract
- A novel wide-field electron arc technique with a scatterer is implemented for widespread Kaposi’s sarcoma (KS) in the distal extremities. Monte Carlo beam modeling for electron arc beams was established to achieve in-vivo measurement data. We enrolled one patient with recurrent KS on the lower extremities who had been treated with photon radiation therapy. The 4- and 6-MeV electron arc plans were created, and then compared to two photon plans: two opposite photon beam and volumetric modulated arc with bolus. Compared to the two photon techniques, the electron arc plans resulted in superior dose saving to normal organs beneath the skin region, although it shows inferior coverage and homogeneity for PTV. The electron arc treatment technique with scatterer was successfully implemented for the treatment of widespread KS in the distal extremities with lower radiation exposure to the normal organs beyond the skin lesions, which could be a treatment option for recurrent skin cancer in the extremities.
- Subjects :
- Materials science
Skin Neoplasms
Photon radiation therapy
lcsh:Medicine
Recurrent skin cancer
Electron
Imaging phantom
Article
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
Dose saving
medicine
Proton Therapy
Skin cancer
Humans
Photon beam
lcsh:Science
Kaposi's sarcoma
Sarcoma, Kaposi
Multidisciplinary
business.industry
Foot
Phantoms, Imaging
Radiotherapy Planning, Computer-Assisted
lcsh:R
Sarcoma
Radiotherapy Dosage
medicine.disease
Hand
Wide field
030220 oncology & carcinogenesis
lcsh:Q
Nuclear medicine
business
Monte Carlo Method
Subjects
Details
- Language :
- English
- ISSN :
- 20452322
- Volume :
- 10
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....a79803678ab4ccb2e74ff3f2931297e1