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Clinical implementation of a wide-field electron arc technique with a scatterer for widespread Kaposi’s sarcoma in the distal extremities

Authors :
Jeongtae Soh
Si Yeol Song
Byungchul Cho
Sang-wook Lee
Changhwan Kim
Chiyoung Jeong
Seonyeong Noh
Seungryong Cho
Minsik Lee
Jungwon Kwak
Minji Koh
Min-Seok Cho
Sung-woo Kim
Source :
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020), Scientific Reports
Publication Year :
2020
Publisher :
Nature Publishing Group, 2020.

Abstract

A novel wide-field electron arc technique with a scatterer is implemented for widespread Kaposi’s sarcoma (KS) in the distal extremities. Monte Carlo beam modeling for electron arc beams was established to achieve in-vivo measurement data. We enrolled one patient with recurrent KS on the lower extremities who had been treated with photon radiation therapy. The 4- and 6-MeV electron arc plans were created, and then compared to two photon plans: two opposite photon beam and volumetric modulated arc with bolus. Compared to the two photon techniques, the electron arc plans resulted in superior dose saving to normal organs beneath the skin region, although it shows inferior coverage and homogeneity for PTV. The electron arc treatment technique with scatterer was successfully implemented for the treatment of widespread KS in the distal extremities with lower radiation exposure to the normal organs beyond the skin lesions, which could be a treatment option for recurrent skin cancer in the extremities.

Details

Language :
English
ISSN :
20452322
Volume :
10
Issue :
1
Database :
OpenAIRE
Journal :
Scientific Reports
Accession number :
edsair.doi.dedup.....a79803678ab4ccb2e74ff3f2931297e1