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An automated microfluidic platform for the screening and characterization of novel hepatitis B virus capsid assembly modulators

Authors :
Tamás Vermes
Mark Kielpinski
Thomas Henkel
Miquel A. Pericàs
Esther Alza
Angelica Corcuera
Helmut Buschmann
Thomas Goldner
Andreas Urban
Source :
Analytical Methods

Abstract

A fully automated microfluidic system was developed to screen for novel anti-HBV capsid assembly modulators. High-resolution dose–response curves were generated using convection-dominated Taylor–Aris dispersion of the screening compounds.

Details

Language :
English
ISSN :
17599679 and 17599660
Volume :
14
Issue :
2
Database :
OpenAIRE
Journal :
Analytical Methods
Accession number :
edsair.doi.dedup.....a7b60143c556826395c038e5eb226ba7
Full Text :
https://doi.org/10.1039/d1ay01227d