Large-scale production of Extracellular Vesicles: report on the 'massivEVs' ISEV workshop

Extracellular vesicles large-scale production is a crucial point for the translation of EVs from discovery to application of EV-based products. In October 2021, the International Society for Extracellular Vesicles (ISEV), along with support by the FET-OPEN projects, evFOUNDRY and VES4US, organized a workshop entitled “massivEVs” to discuss the potential challenges for translation of EV-based products. This report gives an overview of the topics discussed during “massivEVs”, the most important points raised, and the points of consensus reached after active discussion among academia and industry representatives. Overall, the review of the existing EV manufacturing and upscaling challenges and the directions for their resolution highlighted in the workshop was constructive and painted an optimistic future for the dynamically expanding EV field.
Journal DOI: https://doi.org/10.1002/jex2.63