Back to Search
Start Over
Etiologic Agents of Bacterial Sepsis and Their Antibiotic Susceptibility Patterns among Patients Living with Human Immunodeficiency Virus at Gondar University Teaching Hospital, Northwest Ethiopia
- Source :
- BioMed Research International, Vol 2016 (2016), BioMed Research International
- Publication Year :
- 2016
- Publisher :
- Hindawi Limited, 2016.
-
Abstract
- Background. Bacterial sepsis is a major cause of illness in human immunodeficiency virus infected patients. There is scarce evidence about sepsis among HIV patients in Ethiopia. This study aimed to determine the etiologic agents of bacterial sepsis and their antibiotic susceptibility patterns among HIV infected patients.Methods. A cross-sectional study was carried out from March 1 to May 2, 2013. One hundred patients infected with HIV and suspected of having sepsis were included. Sociodemographic data were collected by interview and blood sample was aseptically collected from study participants. All blood cultures were incubated aerobically at 35°C and inspected daily for 7 days. The positive blood cultures were identified following the standard procedures and antimicrobial susceptibility testing was performed using disk diffusion technique. Data was entered by Epi-info version 3.5.1 and analysis was done using SPSS version 20.Results. Of the study participants, 31 (31%) confirmed bacterial sepsis. The major isolates were 13 (13%)Staphylococcus aureus, 8 (8%) coagulates negative staphylococci, and 3 (3%) viridans streptococci. Majority of the isolates, 25 (80.6%), were multidrug resistant to two or more antimicrobial agents.Conclusions. Bacterial sepsis was a major cause of admission for HIV infected patients predominated byStaphylococcus aureusand coagulase negative staphylococci species and most of the isolates were multidrug resistant.
- Subjects :
- 0301 basic medicine
Adult
Male
medicine.medical_specialty
Staphylococcus aureus
Article Subject
Adolescent
medicine.drug_class
030106 microbiology
Antibiotics
lcsh:Medicine
HIV Infections
medicine.disease_cause
Staphylococcal infections
General Biochemistry, Genetics and Molecular Biology
Sepsis
03 medical and health sciences
0302 clinical medicine
Internal medicine
Drug Resistance, Bacterial
medicine
Humans
030212 general & internal medicine
Child
Hospitals, Teaching
General Immunology and Microbiology
biology
business.industry
lcsh:R
Infant
General Medicine
Middle Aged
Staphylococcal Infections
medicine.disease
biology.organism_classification
Antimicrobial
Multiple drug resistance
Cross-Sectional Studies
Viridans streptococci
Child, Preschool
Immunology
HIV-1
Female
Ethiopia
Coagulase
business
Research Article
Subjects
Details
- Language :
- English
- ISSN :
- 23146141 and 23146133
- Volume :
- 2016
- Database :
- OpenAIRE
- Journal :
- BioMed Research International
- Accession number :
- edsair.doi.dedup.....a868f8929dfdccf5a9d5d4e006956ae0