Back to Search
Start Over
Positron Emission Tomography in Thymic Tumors: Analysis Using a Prospective Research Database
- Source :
- The Annals of Thoracic Surgery. 104:1815-1820
- Publication Year :
- 2017
- Publisher :
- Elsevier BV, 2017.
-
Abstract
- Background Positron emission tomography may have a role in the pretreatment workup of patients with thymic malignancies. This study was undertaken to determine the utility of the maximum standardized uptake value (SUVmax) in predicting histologic type and tumor stage in a large cohort of thymic epithelial tumors. Methods The large, multiinstitutional, prospective database of The International Thymic Malignancy Interest Group (ITMIG) was queried for the use of positron emission tomography in the pretreatment workup of patients with thymic tumors. Data analyzed included demographics, SUVmax, histologic tumor type, and tumor stage. The distribution of SUVmax according to histologic type and Masaoka-Koga pathologic stage was determined, and the ability of SUVmax to predict these two variables was calculated using analysis of receiver operating characteristic curves. Results Since 2012, data from 926 patients with thymic malignancies were entered into the ITMIG prospective database, of which 154 had a reported value for SUVmax. The area under the receiver operating characteristic curve for SUVmax in predicting histologic type and pathologic stage was 0.79 (95% confidence interval, 0.70 to 0.88; p Conclusions Positron emission tomography has utility in predicting clinicopathologic features of thymic malignancies. These results may have clinical application in the pretreatment workup of patients with these rare tumors.
- Subjects :
- Male
Pulmonary and Respiratory Medicine
Databases, Factual
Thymic Tumors
Standardized uptake value
030204 cardiovascular system & hematology
computer.software_genre
Malignancy
Article
03 medical and health sciences
0302 clinical medicine
Predictive Value of Tests
medicine
Humans
Neoplasm Invasiveness
Neoplasms, Glandular and Epithelial
Prospective Studies
Prospective cohort study
Neoplasm Staging
Database
Receiver operating characteristic
medicine.diagnostic_test
business.industry
Thymus Neoplasms
Middle Aged
medicine.disease
Confidence interval
ROC Curve
Positron emission tomography
Positron-Emission Tomography
030220 oncology & carcinogenesis
Predictive value of tests
Female
Surgery
Cardiology and Cardiovascular Medicine
Nuclear medicine
business
computer
Subjects
Details
- ISSN :
- 00034975
- Volume :
- 104
- Database :
- OpenAIRE
- Journal :
- The Annals of Thoracic Surgery
- Accession number :
- edsair.doi.dedup.....a878dfb0094602d2091b68d8d4f25698
- Full Text :
- https://doi.org/10.1016/j.athoracsur.2017.06.053