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Baricitinib as rescue therapy in a patient with COVID-19 with no complete response to sarilumab
- Source :
- Infection
- Publication Year :
- 2020
-
Abstract
- A patient with COVID-19-related severe respiratory failure, with insufficient response to an antiretroviral therapy, hydroxychloroquine and Interleukin-6 (IL-6) antagonist therapy, presented a prompt resolution of the respiratory function and improvement in the radiological picture after baricitinib at an oral dose of 4 mg per day for 2 weeks.
- Subjects :
- 0301 basic medicine
Male
Baricitinib
medicine.medical_treatment
Azithromycin
Lopinavir
0302 clinical medicine
Respiratory function
030212 general & internal medicine
Sulfonamides
Brief Report
General Medicine
Drug Combinations
Infectious Diseases
Treatment Outcome
Radiological weapon
Anesthesia
Acute Disease
Immunotherapy
Coronavirus Infections
Respiratory Insufficiency
medicine.drug
Hydroxychloroquine
Microbiology (medical)
Coronavirus disease 2019 (COVID-19)
030106 microbiology
Pneumonia, Viral
Antibodies, Monoclonal, Humanized
Antiviral Agents
03 medical and health sciences
Betacoronavirus
medicine
Humans
Pandemics
Aged
Ritonavir
business.industry
SARS-CoV-2
Sarilumab
Drug Repositioning
COVID-19
Respiratory failure
Purines
Azetidines
Pyrazoles
business
Subjects
Details
- ISSN :
- 14390973
- Volume :
- 48
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Infection
- Accession number :
- edsair.doi.dedup.....a8f756b07f934d5759f68ffcf9c31b73