Physiologically based pharmacokinetic modelling to predict the pharmacokinetics of metoprolol in different CYP2D6 genotypes

Authors :: Choong-Min Lee
Pureum Kang
Chang‑Keun Cho
Hye-Jung Park
Yun Jeong Lee
Jung‑Woo Bae
Chang-Ik Choi
Hyung Sik Kim
Choon-Gon Jang
Seok-Yong Lee
Source :: Archives of Pharmacal Research. 45:433-445
Publication Year :: 2022
Publisher :: Springer Science and Business Media LLC, 2022.
Abstract: Metoprolol, a selective β

Subjects :: Cytochrome P-450 CYP2D6
Genotype
Pharmacogenetics
Hypertension
Organic Chemistry
Drug Discovery
Humans
Molecular Medicine
Metoprolol

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