Duration of carbapenemase-producing enterobacteriaceae carriage in hospital patients

To determine the duration of carbapenemase-producing Enterobacteriaceae (CPE) carriage, we studied 21 CPE carriers for »1 year. Mean carriage duration was 86 days; probability of decolonization in 1 year was 98.5%, suggesting that CPE-carriers' status can be reviewed yearly. Prolonged carriage was associated with use of antimicrobial drugs. Ministry of Education (MOE) National Medical Research Council (NMRC) Published version The study is primarily supported by the Singapore Biomedical Research Council–Economic Development Board Industry Alignment Fund (grant no. IAF311018). M.Y. is supported by the Singapore National Medical Research Council (NMRC) Research Fellowship (grant no. NMRC/Fellowship/0051/2017). B.S.C. is supported by the UK Medical Research Council/Department for International Development (grant no. MR/K006924/1). P.M. is supported by the Joint Programming Initiativeon Antimicrobial Resistance (MODERN) (grant no. C-17-0014). A.H. is supported by Wellcome Trust (grant no. 212630/Z/18/Z). The Mahidol-Oxford Tropical Medicine Research Unit is part of the Wellcome-Trust Major Overseas Programme in Southeast Asia (grant no. 106698/Z/14/Z).Additional grant support was provided by the NMRC Clinician-Scientist Individual Research Grant (grant no. NMRC/CIRG/1463/2016 and NMRC/CIRG/1467/2017); the Singapore Ministry of Education Academic Research Fund Tier 2 grant, New Delhi Metallo-Beta-Lactamase, a global multi-centre, whole-genome study (grant no. MOE2015-T2-2-096); an NMRC collaborative grant, Collaborative Solutions Targeting Antimicrobial Resistance Threats in Health Systems (grant no. NMRC CGAug16C005); and an NMRC Clinician Scientist Award (grant no. NMRC/CSA-INV/0002/2016).