Hepatitis Associated Antigen in Various Clinical Conditions Especially in Primary Hepatome and Metastatic Liver Cancer

Hepatitis associated antigen (HB Ag) was measured using a single radial immunodiffusion (SRID) method or an immunoadherent hemag-glutination (IAHA) method in patients under various clinical conditions including acute hepatitis, chronic hepatitis, liver cirrhosis, hepatoma, various malignant tumors and other diseases as well as in normal subjects. HB Ag was found to be frequently positive in patients with hepatoma and with malignant tumor with liver metastasis by the immunoadherent hemagglutination method. The significance of this finding is discussed.