Back to Search
Start Over
Solitary median maxillary central incisor with congenital strabismus and autoimmune thyroiditis in a young child
- Source :
- BMJ Case Rep
- Publication Year :
- 2023
-
Abstract
- Single median maxillary central incisor (SMMCI) syndrome is rare. It is commonly associated with other midline defects. About 50% of children with SMMCI have short stature, associated with isolated growth hormone deficiency or panhypopituitarism.A 6-year-old girl presented to us with worsening convergent squint, slowing linear growth and a suspected pituitary macroadenoma on neuroimaging. The key findings on examination included a disproportionate short stature, SMMCI, congenital abduction defect and pseudohypertrophy of calf muscles with myopathy. The evaluation showed autoimmune thyroiditis with pituitary hyperplasia. Bone age corresponded to 3 years.Three months after initiation of thyroxine, her myopathy resolved, and the hormone profile and neuroimaging were normal. Autoimmune thyroiditis in association with SMMCI is not reported previously. This case study emphasises the importance of growth monitoring and the exclusion of common treatable conditions.
- Subjects :
- Pediatrics
medicine.medical_specialty
Congenital strabismus
030209 endocrinology & metabolism
Case Report
Short stature
Autoimmune thyroiditis
03 medical and health sciences
0302 clinical medicine
Holoprosencephaly
medicine
Maxilla
Humans
Myopathy
Child
Anodontia
business.industry
Thyroid disease
Cranial nerves
Thyroiditis, Autoimmune
Bone age
General Medicine
Syndrome
medicine.disease
Incisor
Strabismus
030221 ophthalmology & optometry
Female
medicine.symptom
business
Hormone
Subjects
Details
- ISSN :
- 1757790X
- Volume :
- 14
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- BMJ case reports
- Accession number :
- edsair.doi.dedup.....a9b74636f57b40778e7eb81b061fa46e