Back to Search Start Over

Solitary median maxillary central incisor with congenital strabismus and autoimmune thyroiditis in a young child

Authors :
Rathika Damodara Shenoy
Tom Alex
Source :
BMJ Case Rep
Publication Year :
2023

Abstract

Single median maxillary central incisor (SMMCI) syndrome is rare. It is commonly associated with other midline defects. About 50% of children with SMMCI have short stature, associated with isolated growth hormone deficiency or panhypopituitarism.A 6-year-old girl presented to us with worsening convergent squint, slowing linear growth and a suspected pituitary macroadenoma on neuroimaging. The key findings on examination included a disproportionate short stature, SMMCI, congenital abduction defect and pseudohypertrophy of calf muscles with myopathy. The evaluation showed autoimmune thyroiditis with pituitary hyperplasia. Bone age corresponded to 3 years.Three months after initiation of thyroxine, her myopathy resolved, and the hormone profile and neuroimaging were normal. Autoimmune thyroiditis in association with SMMCI is not reported previously. This case study emphasises the importance of growth monitoring and the exclusion of common treatable conditions.

Details

ISSN :
1757790X
Volume :
14
Issue :
2
Database :
OpenAIRE
Journal :
BMJ case reports
Accession number :
edsair.doi.dedup.....a9b74636f57b40778e7eb81b061fa46e