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Resettable skin interfaced microfluidic sweat collection devices with chemesthetic hydration feedback
- Source :
- Nature Communications, Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
- Publication Year :
- 2019
- Publisher :
- Nature Publishing Group UK, 2019.
-
Abstract
- Recently introduced classes of thin, soft, skin-mounted microfluidic systems offer powerful capabilities for continuous, real-time monitoring of total sweat loss, sweat rate and sweat biomarkers. Although these technologies operate without the cost, complexity, size, and weight associated with active components or power sources, rehydration events can render previous measurements irrelevant and detection of anomalous physiological events, such as high sweat loss, requires user engagement to observe colorimetric responses. Here we address these limitations through monolithic systems of pinch valves and suction pumps for purging of sweat as a reset mechanism to coincide with hydration events, microstructural optics for reversible readout of sweat loss, and effervescent pumps and chemesthetic agents for automated delivery of sensory warnings of excessive sweat loss. Human subject trials demonstrate the ability of these systems to alert users to the potential for dehydration via skin sensations initiated by sweat-triggered ejection of menthol and capsaicin.<br />Wearables capable of collecting and analyzing sweat are of interest for athletics and health monitoring. Here, the authors report a resettable microfluidic platform comprising soft pumps and valves that provides triggered release of chemesthetic agents to alert the user of excessive sweat loss.
- Subjects :
- 0301 basic medicine
Computer science
Science
Microfluidics
Active components
General Physics and Astronomy
Organism Hydration Status
02 engineering and technology
Biosensing Techniques
General Biochemistry, Genetics and Molecular Biology
Article
SWEAT
03 medical and health sciences
User engagement
Humans
lcsh:Science
Sweat
Monitoring, Physiologic
Skin
Feedback, Physiological
Multidisciplinary
integumentary system
Reproducibility of Results
General Chemistry
Electrochemical Techniques
Microfluidic Analytical Techniques
021001 nanoscience & nanotechnology
Mechanical engineering
030104 developmental biology
lcsh:Q
Fluidics
0210 nano-technology
Reset (computing)
Biomedical engineering
Biomarkers
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Nature Communications
- Accession number :
- edsair.doi.dedup.....aa921e55fe645fff2872c5e8dd3215dd