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Effects of Scleral-lens Tear Clearance on Corneal Edema and Post-lens Tear Dynamics: A Pilot Study
- Source :
- Optometry and vision science : official publication of the American Academy of Optometry, vol 95, iss 6
- Publication Year :
- 2018
- Publisher :
- eScholarship, University of California, 2018.
-
Abstract
- Author(s): Tan, Bo; Zhou, Yixiu; Yuen, Tiffany L; Lin, Kristina; Michaud, Langis; Lin, Meng C | Abstract: SignificanceThe present study with small-diameter scleral lenses (SLs) revealed that post-lens tear thickness (PoLTT) was significantly associated with post-lens tear mixing, but not with central corneal edema, after short-term SL wear.PurposeThe aim of this study was to investigate the influence of SL tear clearance (PoLTT) on central corneal thickness and post-lens tear dynamics during 5-hour lens wear.MethodsNeophytes with no active ocular disease were fitted bilaterally with SLs (hofocon A; 15.6-mm diameter; ~438-μm thickness; 97 Dk; 1.44 refractive index) with various initial PoLTT values ranging from 74 to 543 μm. Central corneal thickness and PoLTT were measured using optical coherence tomography during lens wear. Tear mixing was assessed using fluorogram and "out-in" method.ResultsThe mean central corneal edema after 5-hour lens wear was 1.51% (95% confidence interval, 1.26 to 1.76%; P l .001), reached its peak at 2-hour post-lens insertion (1.65% [95% confidence interval, 1.45 to 1.85%]), and was independent of PoLTT. The fastest fluorescence decay of the post-lens tear film was observed superiorly. The fluorescence decay rate increased from center to periphery in all quadrants except superiorly. An inverse relationship was found between PoLTT and fluorescence decay rate at both 20-minute and 5-hour wear after lens insertion (P l .05). Excluding observations with out-in time exceeding 5 minutes, we found a direct relationship between PoLTT at 20 minutes after lens insertion and out-in time (P = .047). The % change in the PoLTT after 5-hour wear was greater with a thinner initial tear clearance than those with a thicker one (P = .034).ConclusionsWithin our study parameters, a thinner PoLTT under a small-diameter SL was associated with faster PoLTT mixing. However, there was no relationship between PoLTT and central corneal thickness during 5-hour SL wear.
- Subjects :
- Male
medicine.medical_specialty
Materials science
Time Factors
Contact Lenses
Pilot Projects
Ophthalmology & Optometry
Medical and Health Sciences
Cornea
03 medical and health sciences
Young Adult
0302 clinical medicine
Scleral lens
Corneal edema
Double-Blind Method
Ophthalmology
medicine
Humans
Prospective Studies
Ocular disease
Tomography
Cross-Over Studies
Corneal Edema
Reproducibility of Results
Organ Size
eye diseases
Sclera
medicine.anatomical_structure
Optical Coherence
Lens (anatomy)
Tears
030221 ophthalmology & optometry
Female
sense organs
Tomography, Optical Coherence
030217 neurology & neurosurgery
Optometry
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- Optometry and vision science : official publication of the American Academy of Optometry, vol 95, iss 6
- Accession number :
- edsair.doi.dedup.....aa996f9881048e9a8c00f0203b888bb9