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Double-blind Cross-over Study of Ketoprofen and Ibuprofen in Management of Rheumatoid Arthritis
- Source :
- BMJ. 4:82-84
- Publication Year :
- 1973
- Publisher :
- BMJ, 1973.
-
Abstract
- A double-blind cross-over study of ketoprofen (Orudis) 150 mg daily and ibuprofen (Brufen) 1,200 mg daily was carried out in 35 outpatients with rheumatoid arthritis. Results suggest that analgesic and anti-inflammatory activity of ketoprofen is superior to that of ibuprofen. Significantly greater pain relief (P < 0·05) and reduction in joint circumference (P < 0·01) was obtained with ketoprofen than with ibuprofen. Side effects of the drugs were comparable and not serious.
- Subjects :
- Adult
Male
Ketoprofen
Analgesic
Anti-Inflammatory Agents
Pain
Arthritis
Benzoates
Arthritis, Rheumatoid
Double blind
medicine
Humans
Acetaminophen
Aged
General Environmental Science
Analgesics
Clinical Trials as Topic
Phenylpropionates
business.industry
organic chemicals
General Engineering
Papers and Originals
General Medicine
Middle Aged
Ibuprofen
medicine.disease
Crossover study
stomatognathic diseases
Anesthesia
Rheumatoid arthritis
General Earth and Planetary Sciences
Female
business
medicine.drug
Subjects
Details
- ISSN :
- 14685833 and 09598138
- Volume :
- 4
- Database :
- OpenAIRE
- Journal :
- BMJ
- Accession number :
- edsair.doi.dedup.....aa9ada60e260cb9a7fe004d26181390d