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Observational Study of Peritoneal Washing Cytology-Positive Gastric Cancer without Gross Peritoneal Metastasis in Patients who Underwent Radical D2 Gastrectomy
- Source :
- Scientific Reports, Scientific Reports, Vol 10, Iss 1, Pp 1-6 (2020)
- Publication Year :
- 2020
- Publisher :
- Springer Science and Business Media LLC, 2020.
-
Abstract
- Background The clinical features and therapeutic strategies for gastric cancer with positive peritoneal washing cytology but without visible gross peritoneal metastasis have not been defined. The aim of this study was to evaluate the effect and clinical prognostic value of postoperative chemotherapy in gastric cancer patients with positive peritoneal washing cytology without gross peritoneal metastasis who underwent radical D2 gastrectomy in terms of disease-free survival (DFS) and overall survival (OS). Materials and Methods Intraoperative peritoneal washing cytology was performed in 285 patients who underwent radical D2 gastrectomy between April 2004 and May 2016. Of them, 88 patients with positive cytology but without gross peritoneal metastasis were included in the study. In total, 64 patients received postoperative chemotherapy, whereas 24 patients underwent surgery only. Results Most gastric cancer patients with positive cytology without gross peritoneal metastasis demonstrated pT4 and/or pN3 disease. Postoperative chemotherapy improved DFS and OS compared to surgery only in gastric cancer patients with positive cytology without gross peritoneal metastasis (median DFS 11.63 vs. 6.98 months, p p p p
- Subjects :
- Male
0301 basic medicine
medicine.medical_specialty
Peritoneal metastasis
Cytodiagnosis
medicine.medical_treatment
D2 gastrectomy
lcsh:Medicine
Gastroenterology
Article
Disease-Free Survival
Gastrointestinal cancer
03 medical and health sciences
0302 clinical medicine
Gastrectomy
Stomach Neoplasms
Cytology
Internal medicine
Humans
Medicine
Peritoneal Lavage
In patient
lcsh:Science
Peritoneal Neoplasms
Neoplasm Staging
Proportional Hazards Models
Retrospective Studies
Chemotherapy
Multidisciplinary
business.industry
lcsh:R
Hazard ratio
Cancer
Middle Aged
Prognosis
medicine.disease
Peritoneal washing
030104 developmental biology
030220 oncology & carcinogenesis
lcsh:Q
Female
Peritoneum
Gastric cancer
business
Subjects
Details
- ISSN :
- 20452322
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....aabf6a977d5602f813150fa2f13f99cf