Antibody activity in various classes of hedgehog immunoglobulins

1. 1. Antibodies of IgM class reacting with rabbit red cells were shown to be present in serum from non-immunized hedgehogs. 2. 2. Antibodies of IgM, IgG1 and IgG2 class reacting with rabbit red cells were shown to be present in serum from hedgehogs immunized with the serum sickness antigen (sheep red cells). 3. 3. Antibody activity to rabbit red cells was not demonstrated in hedgehog IgA.