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Global epidemiology of non-influenza RNA respiratory viruses: data gaps and a growing need for surveillance
- Source :
- The Lancet Infectious Diseases, The Lancet Infectious Diseases, New York, NY : Elsevier Science ; The Lancet Pub. Group, 2001-, 2017, 17 (10), pp.e320-e326. ⟨10.1016/S1473-3099(17)30238-4⟩, Lancet Infectious Diseases, 17(10), E320-E326. Lancet Publishing Group
- Publication Year :
- 2017
- Publisher :
- Lancet Publishing Group, 2017.
-
Abstract
- International audience; Together with influenza, the non-influenza RNA respiratory viruses (NIRVs), which include respiratory syncytial virus, parainfluenza viruses, coronavirus, rhinovirus, and human metapneumovirus, represent a considerable global health burden, as recognised by WHO's Battle against Respiratory Viruses initiative. By contrast with influenza viruses, little is known about the contemporaneous global diversity of these viruses, and the relevance of such for development of pharmaceutical interventions. Although far less advanced than for influenza, antiviral drugs and vaccines are in different stages of development for several of these viruses, but no interventions have been licensed. This scarcity of global genetic data represents a substantial knowledge gap and impediment to the eventual licensing of new antiviral drugs and vaccines for NIRVs. Enhanced genetic surveillance will assist and boost research and development into new antiviral drugs and vaccines for these viruses. Additionally, understanding the global diversity of respiratory viruses is also part of emerging disease preparedness, because non-human coronaviruses and paramyxoviruses have been listed as priority concerns in a recent WHO research and development blueprint initiative for emerging infectious diseases. In this Personal View, we explain further the rationale for expanding the genetic database of NIRVs and emphasise the need for greater investment in this area of research.
- Subjects :
- 0301 basic medicine
medicine.medical_specialty
viruses
MESH: Global Health
Disease
medicine.disease_cause
Virus
MESH: Population Surveillance
03 medical and health sciences
0302 clinical medicine
Human metapneumovirus
[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases
Epidemiology
medicine
Global health
030212 general & internal medicine
Coronavirus
[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases
MESH: Humans
biology
virus diseases
[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology
biology.organism_classification
Virology
3. Good health
030104 developmental biology
Infectious Diseases
Preparedness
MESH: Respiratory Tract Infections
[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
Rhinovirus
MESH: RNA Viruses
Subjects
Details
- ISSN :
- 14744457 and 14733099
- Volume :
- 17
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- The Lancet Infectious Diseases
- Accession number :
- edsair.doi.dedup.....aafa2998b8a283a601266aac69750ab2